Ontology
comment: This is an experimental ontology for hypertension. Developed by Hanfei Bao, BMKI Lab.

canIncrease
type: ObjectProperty
inverse of: isIncreasedBy

canDecrease
type: ObjectProperty
inverse of: isDecreasedBy

isIncreasedBy
type: ObjectProperty

isDecreasedBy
type: ObjectProperty

canStimulate
type: ObjectProperty

isStimulatedBy
type: ObjectProperty
inverse of: canStimulate

hasComponent
type: ObjectProperty

hasPart
type: ObjectProperty
sub property of: hasComponent

hasAssociatedFactor
type: ObjectProperty

hasCauseFactor
type: ObjectProperty
sub property of: hasAssociatedFactor

hasResultFactor
type: ObjectProperty
sub property of: hasAssociatedFactor

isComponentOf
type: ObjectProperty

isFunctionOf
type: ObjectProperty
sub property of: isComponentOf

isPartOf
type: ObjectProperty
comment: isPartOf would be limited to the physical parts of a thing
sub property of: isComponentOf

hasSymptom
type: ObjectProperty

hasOperand
type: ObjectProperty

hasMenuend
type: ObjectProperty
sub property of: hasOperand

hasSubtrahend
type: ObjectProperty
sub property of: hasOperand

isCausedBy
type: ObjectProperty

hasNotObjectValue
type: ObjectProperty
comment: An object property indicating the nonexistent of object values.

canCause
type: ObjectProperty
inverse of: isCausedBy

canGenerateOrFacilitate
type: ObjectProperty

canGenerate
type: ObjectProperty

canFacilitate
type: ObjectProperty
sub property of: canGenerateOrFacilitate

hasIndication
type: ObjectProperty

hasContraindication
type: ObjectProperty

hasNumericValue
type: DatatypeProperty
comment: a datatype property linking an idividual to a numerical value.

hasFeature
type: DatatypeProperty

BiologicalEvent
type: Class
subclass of: Thing
comment: This notion includes the change happening in the human body.

SecretionOfRenin
type: Class
subclass of: Secretion

HeartFailure
type: Class
subclass of: HeartDisease

Secretion
type: Class
subclass of: BiologicalMechanismOrFunctionOrParameters

Volume
type: Class
subclass of: BiologicalMechanismOrFunctionOrParameters

BloodVolume
type: Class
subclass of: Volume

BloodVolumeOfKidney
type: Class
subclass of: BloodVolume

DecreasedBloodVolumeOfKidney
type: Class
subclass of: BloodVolumeOfKidney

Reproduction
type: Class
subclass of: BiologicalMechanismOrFunctionOrParameters

Pregnancy
type: Class
subclass of: Reproduction

BodyOrgan
type: Class
subclass of: BiologicalStructure

BodySystem
type: Class
subclass of: BiologicalStructure

Liver
type: Class
subclass of: BodyOrgan

Lungs
type: Class
subclass of: BodyOrgan

StructureInBodyOrgan
type: Class
subclass of: BiologicalStructure

AntihypertensiveDrug
type: Class
subclass of: Drug

BiologicalMechanismOrFunctionOrParameters
type: Class
subclass of: Thing
comment: An domain proper axis, which includes biochemical or physiological mechansims or functions or parameters in human body rather than those at whole body level. l

HereditySusceptibility
type: Class
subclass of: BiologicalMechanismOrFunctionOrParameters

Degree
type: Class
subclass of: Modifier

AfricanAmerican
type: Class
subclass of: Person

IsolatedSystolicHypertension
type: Class
subclass of: Hypertension

MildHypokalemia
type: Class
subclass of: Hypokalemia
subclass of: Restriction
  on property: hasNotObjectValue
  some values from: Symptom

GeneralSubstance
type: Class
subclass of: Thing
disjoint with: HumanAction
comment: A general independent axis which covers the all general substances rather than those as intrinsic biochemical or physiological elements in human body.

Drug
type: Class
subclass of: GeneralSubstance

ModerateHypokalemia
type: Class
subclass of: Hypokalemia
subclass of: Restriction
  on property: hasSymptom
  some values from: CrampDuringExercise
subclass of: Restriction
  on property: hasSymptom
  some values from: Confusion
subclass of: Restriction
  on property: hasSymptom
  some values from: DiscomfortOfMuscle
subclass of: Restriction
  on property: hasSymptom
  some values from: Disorientation
subclass of: Restriction
  on property: hasSymptom
  some values from: Weakness

SevereHypokalemia
type: Class
subclass of: Hypokalemia
subclass of: Restriction
  on property: canCause
  some values from: SevereWeakness
subclass of: Restriction
  on property: canCause
  some values from: PlaccidParalysis
subclass of: Restriction
  on property: canCause
  some values from: DeathFromParalysisOfRespiratoryMuscle
subclass of: Restriction
  on property: canCause
  some values from: DeathFromCardiacArrest
subclass of: Restriction
  on property: canCause
  some values from: Arrhythmia

Confusion
type: Class
subclass of: Symptom

Weakness
type: Class
subclass of: Symptom

Arrhythmia
type: Class
subclass of: HeartDisease

Discomfort
type: Class
subclass of: Symptom

DiscomfortOfMuscle
type: Class
subclass of: Discomfort

Disorientation
type: Class
subclass of: Symptom

ConcentrationOfSerumPotassium
type: Class
subclass of: Variable
comment: Concentration unit: mM

ConcentrationOfSerumPotassiumOfModerateHypokalemia
type: Class
subclass of: ConcentrationOfSerumPotassium
subclass of: Restriction
  on property: hasNumericValue
  some values from: DataRange
    max inclusive: 3.0
    on data range: decimal
subclass of: Restriction
  on property: hasNumericValue
  some values from: DataRange
    min inclusive: 2.5
    on data range: decimal

ConcentrationOfSerumPotassiumOfSevereHypokalemia
type: Class
subclass of: ConcentrationOfSerumPotassium
subclass of: Restriction
  on property: hasNumericValue
  some values from: DataRange
    min exclusive: 2.5
    on data range: decimal

Anxiety
type: Class
subclass of: HumanMentalAction

Stress
type: Class
subclass of: HumanMentalAction

Fear
type: Class
subclass of: HumanMentalAction

WhiteCoatHypertension
type: Class
subclass of: Hypertension
subclass of: Restriction
  on property: isCausedBy
  some values from: Fear
subclass of: Restriction
  on property: isCausedBy
  some values from: Anxiety
subclass of: Restriction
  on property: isCausedBy
  some values from: Stress
comment: Eqaivalent of SCT code 389359009 White Coat Hypertension (disorder)(is a Duplicate concept or inactive conept)

WidenedPulsePressure
type: Class
subclass of: PulsePressure

DiscomfortOfLegWhileSittingStill-Cont
type: Class
subclass of: DiscomfortOfMuscle
comment: 1.a descriptive symptom 2.-Cont: may be relieved by changing leg position or by stomping feet

Hypokalemia
type: Class
subclass of: Disease

Symptom
type: Class
subclass of: AbnormalThing

HumanPhysicalAction
type: Class
subclass of: HumanAction

HumanMentalAction
type: Class
subclass of: HumanAction

SystolicBloodPressureOfHypertension
type: Class
subclass of: SystolicBloodPressure
subclass of: Restriction
  on property: hasNumericValue
  some values from: DataRange
    min inclusive: 140
    on data range: integer

DiastolicBloodPressureOfHypertension
type: Class
subclass of: DiastolicBloodPressure
subclass of: Restriction
  on property: hasNumericValue
  some values from: DataRange
    min inclusive: 90
    on data range: integer

SystolicBloodPressureOfPrehypertension
type: Class
subclass of: SystolicBloodPressure
subclass of: Class
  intersection of: Restriction
    on property: hasNumericValue
    some values from: DataRange
      min exclusive: 120
      on data range: integer
  intersection of: Restriction
    on property: hasNumericValue
    some values from: DataRange
      max exclusive: 140
      on data range: integer

DiastolicBloodPressureOfPrehypertension
type: Class
subclass of: DiastolicBloodPressure
subclass of: Class
  intersection of: Restriction
    on property: hasNumericValue
    some values from: DataRange
      min exclusive: 80
      on data range: integer
  intersection of: Restriction
    on property: hasNumericValue
    some values from: DataRange
      max exclusive: 90
      on data range: integer

BiologicalSubstance
type: Class
subclass of: Thing
comment: A domain proper axis.

BiologicalStructure
type: Class
subclass of: Thing
comment: A domain proper axis, including pysical structures in human body.

Cramp
type: Class
subclass of: Symptom

CardiovascularSystem
type: Class
subclass of: BodySystem

VascularSystem
type: Class
subclass of: CardiovascularSystem

CrampDuringExercise
type: Class
subclass of: Cramp

Artery
type: Class
subclass of: VascularSystem

SevereWeakness
type: Class
subclass of: Weakness

HardenedArtery
type: Class
subclass of: Artery
subclass of: Restriction
  on property: canCause
  some values from: WidenedPulsePressure
comment: 1. can lead to a widened pulse pressure; 2. has a potential sematic relation with Variable-Hardness; 3. has a potential semantic relation with NormalThingOrAbnormalThing-Abnormalzthing.

Paralysis
type: Class
subclass of: Symptom

PlaccidParalysis
type: Class
subclass of: Paralysis

DiabetesMellitus
type: Class
subclass of: Disease

IdealSystolicBloodPressureOfDiabetesMellitus
type: Class
subclass of: IdealSystolicBloodPressure
subclass of: Restriction
  on property: hasNumericValue
  some values from: DataRange
    max exclusive: 130
    on data range: integer

IdealDiastolicBloodPressureOfDiabetesMellitus
type: Class
subclass of: IdealDiastolicBloodPressure
subclass of: Restriction
  on property: hasNumericValue
  some values from: DataRange
    max exclusive: 80
    on data range: integer

PathologicEvent
type: Class
subclass of: AbnormalThing
comment: A sudden and pathological change

IdealSystolicBloodPressureOfChronicKidneyDisease
type: Class
subclass of: IdealSystolicBloodPressure
subclass of: Restriction
  on property: hasNumericValue
  some values from: DataRange
    max exclusive: 130
    on data range: integer

IdealDiastolicBloodPressureOfChronicKidneyDisease
type: Class
subclass of: IdealDiastolicBloodPressure
subclass of: Restriction
  on property: hasNumericValue
  some values from: DataRange
    max exclusive: 80
    on data range: integer

DeathFromParalysisOfRespiratoryMuscle
type: Class
subclass of: PathologicEvent

IdealSystolicBloodPressureOfAfricanAmerican
type: Class
subclass of: IdealSystolicBloodPressure
subclass of: Restriction
  on property: hasNumericValue
  some values from: DataRange
    max exclusive: 135
    on data range: integer

DeathFromCardiacArrest
type: Class
subclass of: PathologicEvent

IdealDiastolicBloodPressureOfAfricanAmerican
type: Class
subclass of: IdealDiastolicBloodPressure
subclass of: Restriction
  on property: hasNumericValue
  some values from: DataRange
    max exclusive: 80
    on data range: integer

CardiogenicShock
type: Class
subclass of: HeartDisease

SystolicBloodPressureOfIsolatedSystolicHypertension
type: Class
subclass of: SystolicBloodPressure
subclass of: Restriction
  on property: hasNumericValue
  some values from: DataRange
    min inclusive: 140
    on data range: integer

UnstableAngina
type: Class
subclass of: AnginaPectoris

Man
type: Class
subclass of: Person

Woman
type: Class
subclass of: Person

AorticStenosis
type: Class
subclass of: Disease

DiastolicBloodPressureOfIsolatedSystolicHypertension
type: Class
subclass of: DiastolicBloodPressure
subclass of: Restriction
  on property: hasNumericValue
  some values from: DataRange
    max exclusive: 90
    on data range: integer

HumanAction
type: Class
subclass of: Thing
disjoint with: Person
disjoint with: Disease
disjoint with: Time
disjoint with: DeviceOrEquipment
comment: A domain proper axis covers the actions of person at whole body level.

BreastFeeding
type: Class
subclass of: HumanPhysicalAction

Person
type: Class
equivalent class: Class
  union of: Man
  union of: Woman
subclass of: Thing
comment: A domain proper axis.

Patient
type: Class
subclass of: Person

Disease
type: Class
subclass of: AbnormalThing
comment: A dorman goal axis.

Time
type: Class
subclass of: Thing
comment: Temporal axis:a general independent axis.

Duration
type: Class
subclass of: Time
disjoint with: Frequency

Severity
type: Class
subclass of: Degree

Frequency
type: Class
subclass of: Time

ConstantOrVariable
type: Class
subclass of: Thing
comment: 1. An independent axis.; 2. a general or high abstract cognitive axis.

Constant
type: Class
subclass of: ConstantOrVariable

Variable
type: Class
subclass of: ConstantOrVariable

DurationOfLabor
type: Class
subclass of: DurationRelatedToPerson

DurationOfGestation
type: Class
subclass of: DurationRelatedToPerson

Hardness
type: Class
subclass of: Variable

Amlodipine
type: Class
subclass of: AntihypertensiveDrug
subclass of: Restriction
  on property: hasIndication
  some values from: AnginaPectoris
subclass of: Restriction
  on property: hasContraindication
  some values from: BreastFeeding
subclass of: Restriction
  on property: hasContraindication
  some values from: CardiogenicShock
subclass of: Restriction
  on property: hasContraindication
  some values from: AorticStenosis
subclass of: Restriction
  on property: hasContraindication
  some values from: UnstableAngina
subclass of: Restriction
  on property: hasIndication
  some values from: Hypertension
comment: The indications include ... The contraindications include ...

HeartDisease
type: Class
subclass of: Disease

PulsePressure
type: Class
subclass of: BiologicalMechanismOrFunctionOrParameters
subclass of: Class
  intersection of: Restriction
    on property: hasMenuend
    some values from: SystolicBloodPressure
  intersection of: Restriction
    on property: hasSubtrahend
    some values from: DiastolicBloodPressure

AnginaPectoris
type: Class
subclass of: HeartDisease

PreHypertension
type: Class
subclass of: Disease

DeviceOrEquipment
type: Class
subclass of: Thing
comment: A general independent axis.

BloodPressureCuff
type: Class
subclass of: DeviceOrEquipment
disjoint with: ContiniousMonitoringEquipForBloodPressure

ContiniousMonitoringEquipForBloodPressure
type: Class
subclass of: DeviceOrEquipment

Hypertension
type: Class
subclass of: Disease
subclass of: Restriction
  on property: hasAssociatedFactor
  some values from: HigherSaltIntake
subclass of: Restriction
  on property: hasAssociatedFactor
  some values from: HereditySusceptibility
subclass of: Restriction
  on property: hasAssociatedFactor
  some values from: Obesity
subclass of: Restriction
  on property: hasAssociatedFactor
  some values from: KidneyFailure
subclass of: Restriction
  on property: hasAssociatedFactor
  some values from: AdvancedAge

PatientWithHypertension
type: Class
subclass of: Patient

PatientWithDiabetesMellitus
type: Class
subclass of: Patient

PatientWithChronicKidneyDesease
type: Class
subclass of: Patient

IdealDiastolicBloodPressure
type: Class
subclass of: DiastolicBloodPressure

KidneyDisease
type: Class
subclass of: Disease

ChronicKidneyDisease
type: Class
subclass of: KidneyDisease

IdealSystolicBloodPressure
type: Class
subclass of: SystolicBloodPressure

PatientWithHypertensionAndDiabetesMellitus
type: Class
subclass of: PatientWithHypertension

PatientWithHypertensionAndChronicKidneyDesease
type: Class
subclass of: PatientWithHypertension

BloodPressure
type: Class
subclass of: BiologicalMechanismOrFunctionOrParameters

SystolicBloodPressure
type: Class
subclass of: BloodPressure

DiastolicBloodPressure
type: Class
subclass of: BloodPressure

Modifier
type: Class
subclass of: BeingModifiedOrModifer
comment: An independent linquistic axis.

LifeStyle
type: Class
subclass of: HumanPhysicalAction

DietStyle
type: Class
subclass of: LifeStyle

HigherSaltIntake
type: Class
subclass of: DietStyle

DurationRelatedToPerson
type: Class
subclass of: Duration

Age
type: Class
subclass of: DurationRelatedToPerson

AdvancedAge
type: Class
subclass of: Age

Obesity
type: Class
subclass of: Disease

KidneyFailure
type: Class
subclass of: KidneyDisease

HypertensionAndDiabetesMellitus
type: Class
subclass of: DiabetesMellitus
subclass of: Hypertension

HypertensionAndChronicKidneyDisease
type: Class
subclass of: Hypertension
subclass of: ChronicKidneyDisease

NormalThing
type: Class
subclass of: NormalThingOrAbnormalThing
disjoint with: AbnormalThing

AbnormalThing
type: Class
subclass of: NormalThingOrAbnormalThing

NormalThingOrAbnormalThing
type: Class
subclass of: Thing
comment: A domain goal axis, interested by the domain.

BeingModifiedOrModifer
type: Class
subclass of: Thing
comment: An independent linquistic axis

BeingModified
type: Class
subclass of: BeingModifiedOrModifer